Not at this time of the year, but walleye run slightly run into some of the larger, better flow tribs mid-March to early April and white suckers run tribs of various sizes around the same time. For walleye Nockamixon, Bucks Co was one example in the past. Raystown is another. Pymatuning is a third, but fishing that trib is prohibited.
Not all lakes have white sucker populations, but some do, such as Kahle Lake, Clarion/Venango Co, Antietam Lake, Berks Co, and many of the larger reservoirs. Some of these sucker runs have attractive fisheries for larger fish at a time of year when people are itching to break the cabin fever.