There's been a lot of discussion of larger watersheds with brook trout populations. Here are two that I haven't seen discussed yet:
Mosquito Creek, Clearfield County.
The upper part of Bowmans Creek, in the State Gamelands, Luzerne County.
Mosquito Creek is infertile and its population is only brookies, no browns or rainbows. It has several tributaries that also hold only brookies. The stream is about 70 feet wide in its middle to lower stretches. It holds brook trout the whole way down to the Quehanna Highway bridge, just above Karthaus, so not very far above the mouth. Mine drainage at that bridge kills it from there to the mouth. Mosquito Creek and Gifford Run, the largest tributary, are stocked.
Bowmans Creek up in the SGLs is also quite a large stream, with several tributaries. Like Mosquito Creek, it's infertile, and the only wild trout I've caught up there were brook trout. There may be a few browns in the lower elevation tribs, I'm not sure. But the whole upper end is infertile and the browns have no chance up there. This is also stocked.
I fished both of these streams when they were unstocked. Liming was done on both watersheds, then the stocking began. On both streams there were plenty of brook trout before the liming. The brook trout population went down hard on both streams as a result of the stocking. There were 2 old ice dams on upper Bowmans, which were removed in recent times. This should benefit water temps and brook trout movement.