Iso's are the summer/fall hatch for the Upper D.
They hatch from June thru Sept/Oct
They are big, like around size 10+/-
Iso's usually hatch sporadically all day. No need to wait for near dark for a hatch, you can prospect with a dry and catch fish on top any time during the day.
They usually crawl out onto rocks to hatch. Check out mid stream rocks in the UDR and you will surely see Iso shucks. I've enough duns floating to believe that they also hatch from the water.
Nymphing with Iso patterns works well in the faster water. The nymphs are fast swimmers, they are cigar shaped, have prominent gills, and often have a light colored stripe down the middle of their back. (see pic below).
To get the proper body shape I tie a nymph pattern using lead wire, either lashed to each side of the hook shank or wound around the shank and squeezed flat. I use dental floss to imitate the light colored stripe along the back.