It depends what you like, Stagger. If you like huge tailwaters and are into the drift boat type stuff, then central PA isn't a real good area. It doesn't have anything on the scale of the Lehigh, D, Yough, or Allegheny.
If you like huge lake or ocean run fish, obviously it's got none of that. There are people in great lakes country, including Erie, PA who laugh at central PA. These guys scoff at an 18 inch trout. "It's just a jack". They expect multiple fish in the mid-20's You could fish a lifetime and never catch an "average" fish in central PA.
If you like remote brookie mountain freestoners, then central PA is alright. But not as attractive as NC PA, or arguably even NW PA, or the eastern side of the state. There are some brookie streams in eastern PA that are truly fantastic and very tough to beat. And in the wild trout mountain stream category, central PA certainly doesn't hold a candle to places like the Smokies.
But, what central PA has is a large number of high quality, medium to large sized, limestoners in a small area, with good hatches and tons of wild trout and generally good public access. If that's what you like, it's probably the best fishing region east of the Mississippi.